mass spectrometry

Extension Activity with Isotopes Matter

After receiving positive feedback from Peter Mahaffy, the IUPAC project co-chair of Isotopes Matter, I decided to add an additional component to the original isotope assignment I posted. The second component of the assignment focuses on the applications of both radioactive and stable isotopes using the interactive IUPAC periodic table.

Time required: 

55-60 minutes for both parts of the extension activity

Mass Spectra

In this Activity, students solve puzzles that are analogous to finding the amino acid sequence of a peptide using mass spectrometry. Students identify words that have been broken into letters or groups of letters. In many textbooks instrumental analysis and various types of spectrometry are mentioned only in passing.