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About CCA!
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| HIV-1 Protease: An Inhibitor as Possible Treatment for AIDS |
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View Slide Thumbnails |
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Voiceover
Let's return to our thrombin demonstration. If a thrombin inhibitor is present in the blood, the effect is completely different from our first demonstration. Here, an inhibitor is added to the blood. Then the thrombin is added.
The inhibitor blocks the active site of the thrombin. Because the thrombin is inhibited, the blood doesn't form a clot.
In the case of HIV, scientists are searching for safe and effective inhibitors for HIV-1 protease. A suitable inhibitor would shut down the reproduction of HIV in the human body. It could be a treatment for HIV and AIDS.
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Citation:
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Jacobsen, E. B.; Jacobsen, J. J.; Wright, J. M.
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J. Chem. Educ. Software HIV-1 Protease: An Enzyme at Work SP13
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Creator:
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Erica Bode Jacobsen
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University of Wisconsin - Madison, Madison, WI 53706
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Executive Producers:
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John W. Moore
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University of Wisconsin - Madison, Madison, WI 53706
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Clark R. Landis
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University of Wisconsin - Madison, Madison, WI 53706
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Support:
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National Science Foundation
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Directorate for Education and Human Resource
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Science Education Scholars Program
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University of Wisconsin - Madison, Madison, WI 53706
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Institute for Chemical Education
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University of Wisconsin - Madison, Madison, WI 53706
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Project Seraphim
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University of Wisconsin - Madison, Madison, WI 53706
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Science Education Advisor:
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Julie Jensen
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Middleton High School, Middleton, WI 53562
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Scientific Support:
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Daniel H. Rich
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University of Wisconsin - Madison, Madison, WI 53706
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Kenneth Satyshur
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University of Wisconsin - Madison, Madison, WI 53706
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Jean-Yves Sgro
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University of Wisconsin - Madison, Madison, WI 53706
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HIV Virion Animation:
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Saviz Artang, George V. Kelvin
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(c) Scientific American Inc. Used by permission
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Writers:
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Erica Bode Jacobsen
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University of Wisconsin - Madison, Madison, WI 53706
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J. Monty Wright
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University of Wisconsin - Madison, Madison, WI 53706
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Kelly Houston Jetzer
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University of Wisconsin - Madison, Madison, WI 53706
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Jerrold J. Jacobsen
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University of Wisconsin - Madison, Madison, WI 53706
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Animation:
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J. Monty Wright
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University of Wisconsin - Madison, Madison, WI 53706
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VISUALITY
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5010 Flambeau Road, Madison, WI 53705
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Video production, editing, and voice:
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Jerrold J. Jacobsen
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University of Wisconsin - Madison, Madison, WI 53706
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Greg Minix
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University of Wisconsin - Madison, College of Engineering, Madison, WI 53706
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Kelly Houston Jetzer
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University of Wisconsin - Madison, Madison, WI 53706
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