Hydrolysis of Wool in Strong Base

CCA! Volume 5

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Hydrolysis of Wool in Strong Base

Concentrated sodium hydroxide breaks the peptide bonds on wool, causing it to dissolve.


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Wool is placed into a solution of hot concentrated sodium hydroxide. Wool is a protein, which is a long chain of amino acids joined by peptide bonds. The sodium hydroxide hydrolyzes the peptide bonds, and the wool is eventually broken down into its amino acids.

Design, Text, and Demonstration:
	Kristin Johnson	University of Wisconsin - Madison, Madison, WI 53706

Video production, editing, and voice:
	Jerrold J. Jacobsen	University of Wisconsin - Madison, Madison, WI 53706
	Greg Minix	University of Wisconsin - Madison, College of Engineering, Madison, WI 53706
	Michael Killips	University of Wisconsin - Madison, School of Nursing, Madison, WI 53706