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About CCA!
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Voiceover
Sodium acetate is added to a dilute solution of DNA. The sodium ions shield the negative charges on the DNA phosphates. This decreases interstrand repulsion and allows the nucleic acids to aggregate. After cold ethanol is added, the DNA precipitates and the solution becomes cloudy. Some of the DNA is wound on a glass rod and removed from the solution.
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Design, Text, and Demonstration:
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Kristin Johnson
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University of Wisconsin - Madison, Madison, WI 53706
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Video production, editing, and voice:
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Jerrold J. Jacobsen
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University of Wisconsin - Madison, Madison, WI 53706
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Greg Minix
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University of Wisconsin - Madison, College of Engineering, Madison, WI 53706
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Michael Killips
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University of Wisconsin - Madison, School of Nursing, Madison, WI 53706
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